Fosfoenolpiruvat karboksikinase
Fosfoenolpiruvat karboksikinase (EC 4.1.1.32) adalah sebuah enzim yang menyintesis glukosa di hati dan ginjal serta sintesis gliserida di jaringan adiposa putih dan usus halus[1] Enzim ini mengatalisis koversi oksaloasetat menjadi fosfoenolpiruvat.[2] Ada dua bentuk isoform dari enzim ini, yaitu bentuk sitosolik dan mitokondria.[3]
Referensi[sunting | sunting sumber]
- ^ Hanson, Richard W.; Reshef, Lea (1997). "REGULATION OF PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP) GENE EXPRESSION". Annual Review of Biochemistry (dalam bahasa Inggris). 66 (1): 581–611. doi:10.1146/annurev.biochem.66.1.581. ISSN 0066-4154.
- ^ Montal, Emily D.; Dewi, Ruby; Bhalla, Kavita; Ou, Lihui; Hwang, Bor Jang; Ropell, Ashley E.; Gordon, Chris; Liu, Wan-Ju; DeBerardinis, Ralph J. (2015-11). "PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth". Molecular Cell. 60 (4): 571–583. doi:10.1016/j.molcel.2015.09.025. ISSN 1097-2765. PMC 4656111
. PMID 26481663.
- ^ Reyes-Ramos, Carlos A.; Peregrino-Uriarte, Alma B.; Cota-Ruiz, Keni; Valenzuela-Soto, Elisa M.; Leyva-Carrillo, Lilia; Yepiz-Plascencia, Gloria (2018-12-01). "Phosphoenolpyruvate carboxykinase cytosolic and mitochondrial isoforms are expressed and active during hypoxia in the white shrimp Litopenaeus vannamei". Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 226: 1–9. doi:10.1016/j.cbpb.2018.08.001. ISSN 1096-4959.
